Quick Navigation

Noopept

Noopept is the brand name for N-phenylacetyl-L-prolylglycine ethyl ester, a Nootropic molecule similar to Piracetam. Noopept may alleviate cognitive decline.

Our evidence-based analysis on noopept features 44 unique references to scientific papers.

Research analysis led by .
Reviewed by
www.blogrefugio.com Team
Last Updated:

Summary of Noopept

Primary information, health benefits, side effects, usage, and other important details

Noopept is the brand name for N-phenylacetyl-L-prolylglycine ethyl ester , a synthetic nootropic molecule.

Noopept has a similar effect to piracetam, in that it provides a mild cognitive boost after supplementation. Noopept also provides a subtle psychostimulatory effect.

Noopept has a much lower standard dose than piracetam (10-30mg, compared to 4800mg), and it provides a general neuroprotective effect after supplementation. This neuroprotective effect occurs during various states of cognitive trauma, including oxidative stress and physical trauma. There is, however, no evidence to suggest Noopept provides benefits for people with no cognitive ailments.

More studies are needed to determine the main mechanisms responsible for Noopept’s neuroprotective effect.

The only human study comparing Noopept and piracetam suggests the two have a comparable effect, once the smaller effective dose is taken into account.

Get trusted answers to health questions that matter to you

Getting an www.blogrefugio.com subscription makes it easy for you to stay informed and understand the latest nutrition research.

If you’re overwhelmed by all the possibilities of supplementation and want step-by-step instructions on what supplements to take (how much, when, and in what combinations), then the www.blogrefugio.com Supplement Guides are perfect for you.

Your support keeps us 100% independent, so that we never have a conflict of interest.


How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

To supplement Noopept, take 10 – 30 mg, once a day, for up to 56 days at a time. More research is needed to determine the optimal human dose for Noopept.

?? Don't waste your time on outdated information: Get Examine Personalized for access to the latest research on 400+ supplements and their effects on 600+ health outcomes.

Already a member? Click here to log in.

Human Effect Matrix

Unlocked for Examine members

The Human Effect Matrix summarizes human studies to tell you what effects Noopept has on your body, how much evidence there is, and how strong these effects are.

Full details are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-d Notable - See study
The one trial with Noopept suggests surprisingly effective rehabilitative effects, outperforming Piracetam as comparator.

Become an Examine Personalized member to access the latest nutrition research on over 400 supplements across more than 600 different health goals, outcomes, conditions, and more.

Becoming an Examine subscriber unlocks the Human Effect Matrix for supplements, as well as all health topics on www.blogrefugio.com. We summarize all the latest research so that you can make the best decisions for your health based on accurate and not up-to-date information.

Plus, you get a monthly summary of the latest research on the health topics you care about.

Things to Note

Is a Form Of

Also Known As

N-phenylacetyl-L-prolylglycine ethyl ester, Noopeptide, Ноопепт, GVS-111

Do Not Confuse With

Piracetam (Basic racetam, but different molecule)

  • Noopept is not technically a racetam molecule (due to not having a 2-oxo-pyrollidine skeleton), but is generally grouped together in the same category

Get our free 5-day course on the essentials of supplementation.

At www.blogrefugio.com, our incentives line up with yours — getting unbiased information. That's why we don’t sell any advertising or supplements.

Join over 250,000 people who have learned about effective versus overrated supplements, tips for buying supplements, and how to combine supplements for safety and efficacy.

Click here to see all 44 references.