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Dry Mouth

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Summary of Dry Mouth

Scientific Information on Dry Mouth

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Dry Mouth.

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Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor Very High See all 4 studies
Symptoms of dry mouth either caused by a disease state (Sjögren's syndrome) or as a side-effect of pharmaceuticals appears to be significantly reduced when betaine is formulated into a toothpaste at 4%. Studies currently have a potential industry influence (financing).
grade-d Notable - See study
A notable reduction in anxiety-associated dry mouth has been noted in one industry-funded study, which needs to be replicated.

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