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Symptoms of the Common Cold

Symptoms of the common cold refer to the actual symptoms experienced during sickness, rather than the risk of developing URTIs or the length of sickness. Reducing symptoms of sickness tends to make the process to health more tolerable despite not actually affecting the healing rate.

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Symptoms of the Common Cold.

Full details on all Symptoms of the Common Cold supplements are available to Examine members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Minor - See all 11 studies
Research is quite mixed and inconsistent, but a small reduction in cold symptoms is likely for some people. The effective dose of echinacea and its active chemicals isn't clear, and more research is needed. It's also not entirely clear which symptoms are reduced, as only one study evaluated specific symptoms, and found a reduction in nasal and sinus symptoms but not cough.
grade-b Minor Very High See all 11 studies
Zinc, particularly >75 mg daily of zinc acetate (more research is needed to confirm the best form and dose) reduces the duration of common colds, and so the time that symptoms are present. It likely has a small effect on the severity of throat and nasal symptoms at any given time, but is less likely to help with headache or fatigue.
grade-c Notable - See study
All symptoms appear to be reduced with treatment of the standard dose of EPs7630. With symptom reduction after five days and the amount of persons with full resolution of symptoms being more than doubled relative to placebo.

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